Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults: Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults

Authors

Gültekin Pekcan Ankara Bilkent City Hospital, Clinic of Hematology, Ankara, Türkiye
Hüseyin Demirci Ankara Etlik City Hospital, Clinic of Endocrinology, Ankara, Türkiye
Fahri Yakaryılmaz Ankara Etlik City Hospital, Clinic of Gastroenterology, Ankara, Türkiye

Keywords:

N-AFLD, non-diabetic, non-obese, serum uric acid, HOMA-IR, metabolic syndrome

Abstract

Objective: Many studies are interested in the association between non-alcoholic fatty liver disease (N-AFLD) and other parameters. Our study evaluated the association between serum uric acid (SrUA) levels and N-AFLD in non-diabetic non-obese adults.

Methods: In this study, 50 patients and 50 control subjects were enrolled to investigate the association between SrUA and N-AFLD in adults. The Kruskal-Wallis test was used to compare SrUA values according to ultrasonographic liver fat levels.

Results: A statistically significant difference was found between the N-AFLD and control subjects according to the mean SrUA level (p<0.001). In the N-AFLD group, a positive relationship was found between SrUA levels and homeostasis model assessment of insulin resistance values (r=0.35, p<0.001).

Conclusion: In this study, an important positive relationship was detected between SrUA levels and N-AFLD and insulin resistance.

Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults