Effect of Vitamin D Supplementation on Body Composition, Depressive Symptoms and Health-Related Quality of Life in Vitamin D Insufficient Healthy AdultsEffect of Vitamin D Supplementation on Body Composition, Depressive Symptoms and Health-Related Quality of Life in Vitamin D Insufficient Healthy Adults

Main Article Content

Kamil İnci
Muhittin YALÇIN
Alev EROĞLU ALTINOVA
Müjde Aktürk
Emine Yassıbaş
Gülşah Şahin
Nevin Şanlıer
Füsun Törüner

Abstract

Objective: Vitamin D deficiency/insufficiency is a high prevalent worldwide health problem in all age groups. Data regarding whether vitamin D insufficiency is assocciated with any effects on body composition, quality of life and depressive symptoms in healthy adults is limited. Our aim was to evaluate the effects of vitamin D supplementation on body composition, depression and health-related quality of life (HRQoL) in vitamin D insufficient healthy adults.


Methods: Thirty-one vitamin D insufficient (serum level <30 ng/ml) healthy participants were included in the study. Bioelectrical impedance analysis (BIA), handgrip strength, Short Form Health Survey 36 (SF-36) scores and Beck depression inventory (BDI) scale were compared before and after 6 months 25 (OH) vitamin D supplementation.


Results: There was statistically significant improvement in both depression scores (19.0 [13-26] vs 8.0 [3-14], p=0.002) and most of HRQoL scoring components (physical functioning (61.0±22.9 vs 69.0±22.0, p=0.02), vitality (30.0 [23-38] vs 55.0 [40-75], p <0.001), bodily pain (52.0 [35-66] vs 74.0 [59-91], p=0.004), physical role functioning (0.0 [0.0-75.0] vs 75.0 [0.0-100], p=0.001), emotional role functioning (0.0 [0-33] vs 67 [0-100.0], p=0.001), social role functioning (37.0 [23-48] vs 50.0 [35-63], p=0.01) and mental health (44.0 [22-56] vs 64.0 [50-78], p=0.002) after vitamin D supplementation. But there were no significant difference in body composition and handgrip strength before and after vitamin D supplementation (p>0.05).


Conclusion: We found that 6 months vitamin D supplementation had positive effects on depressive symptoms and HRQoL, but it didn’t effect body composition and handgrip strength in vitamin D insufficient healthy adults.

Article Details

Section
Original Research
Author Biographies

Muhittin YALÇIN

Division of Endocrinology and Metabolism, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey

Alev EROĞLU ALTINOVA

Division of Endocrinology and Metabolism, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey

Müjde Aktürk

Division of Endocrinology and Metabolism, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey

Emine Yassıbaş

Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University Ankara, Turkey.

Gülşah Şahin

Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University Ankara, Turkey.

Nevin Şanlıer

Faculty of Health Sciences, Nutrition and Dietetics Department, Ankara Medipol University, Ankara, Turkey.

Füsun Törüner

Division of Endocrinology and Metabolism, Department of Internal Medicine, Gazi University School of Medicine, Ankara, Turkey