Skeletal Metastases in Renal Cell Carcinoma: A Peculiar Occurrence after Treatment and Long Term Remission

Main Article Content

Fattah Abdul Hamid
Zainal Adwin Zainal Abiddin
Firdaus Hayati
Fam Xeng Inn
Zulkifli Zainuddin

Abstract

Distant metastases are characteristic for renal cell carcinoma (RCC). Metastases has been observed years after removal of the primary tumor hence the need for surveillance. The most commonly involved sites are the lungs (33-72%), intra-abdominal lymph nodes (3-35%), bone (21-25%), brain (7-13%) and liver (5-10%). Skeletal muscle metastases on the other hand are extremely rare. Our patient presented with uncommon metastasis of RCC to the left brachioradialis, which supports the unpredictable nature of this neoplasm.

Article Details

Section
Case Report
Author Biographies

Fattah Abdul Hamid, Universiti Kebangsaan Malaysia Medical Centre

Urology Unit, Department of Surgery

Zainal Adwin Zainal Abiddin, Faculty of Medicine, Universiti Teknologi MARA

Department of Surgery

Fam Xeng Inn, Universiti Kebangsaan Malaysia Medical Centre

Urology Unit, Department of Surgery

Zulkifli Zainuddin, Universiti Kebangsaan Malaysia Medical Centre

Head of Unit, Urology Unit, Department of Surgery

References

Klatte T, Han KR, Said JW, et al. Pathobiology and prognosis of chromophobe renal cell carcinoma. Urol Oncol. 2008; 26(6):604-9.

Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011; 61:212.

Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012; 62:10.

Chow WH, Dong LM, Devesa SS. Epidemiology and risk factors for kidney Cancer. Nat Rev Urol 2010; 7:245–57.

Seely S. Possible reasons for the high resistance of muscle to cancer. Med Hypotheses 1980; 6: 133–7.

Ali SH, Chughtai H, Alali F, Diaczok B, Verardi M. Wrist drop: an atypical presentation of renal cell carcinoma. Am J Med Sci 2011; 342: 170–3.

Flanigan RC, Campbell SC, Clark JI, Picken MM. Metastatic renal cell carcinoma. Curr Treat Options Oncol 2003; 4: 385–90.

Antonelli A, Arrighi N, Corti S,Legramanti S, Zanotelli T, Cozzoli A, et al. Surgical treatment of atypical metastasis from renal cell carcinoma (RCC). BJU Int 2012; 110: E559–63.

Swanson DA. Surgery for metastases of renal cell carcinoma. Scand J Surg 2004.

Alt AL, Boorjian SA, Lohse CM, Costello BA, Leibovich BC, Blute ML. Survival after complete surgical resection of multiple metastases from renal cell carcinoma. Cancer 2011; 117: 2873–82.