Authors
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Rosli Ismail
Department of Surgery, Selayang Hospital, Ministry of Health Malaysia, Batu Caves, Selangor, Malaysia
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Mohd Firdaus Che Ani
Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Sungai Buloh Campus, Selayang, Selangor, Malaysia
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Salahuddin Baharom
Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Sungai Buloh Campus, Selayang, Selangor, Malaysia
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Nornazirah Azizan
Department of Pathology and Microbiology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
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Andee Dzulkarnaen Zakaria
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Firdaus Hayati
Keywords:
Appendectomy, appendicitis, goblet cell carcinoid
Abstract
Goblet cell carcinoid (GCC) is an enigmatic and rare tumour involving the appendix almost exclusively. It is a rare, aggressive subtype of appendiceal tumours with neuroendocrine features, and controversy exists with regards to therapeutic strategy. We herein highlight a 56-year-old lady with GCC whom she presented initially with a typical presentation of acute appendicitis. The histologic hallmark of this entity is the presence of clusters of goblet cells in the lamina propria or submucosa stain for various neuroendocrine markers, though the intensity is often patchy. GCC of the appendix is rare and challenging. In advanced form, it can present with carcinoid symptoms but occasionally mimics classical presentations of acute appendicitis. A tumour measuring less than 1 cm and located at the tip of the appendix is sufficient for a simple appendicectomy which warrants a promising prognosis.
Author Biographies
Rosli Ismail, Department of Surgery, Selayang Hospital, Ministry of Health Malaysia, Batu Caves, Selangor, Malaysia
Department of Surgery, Selayang Hospital, Ministry of Health Malaysia, Batu Caves, Selangor, Malaysia
Mohd Firdaus Che Ani, Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Sungai Buloh Campus, Selayang, Selangor, Malaysia
Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Sungai Buloh Campus, Selayang, Selangor, Malaysia
Salahuddin Baharom, Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Sungai Buloh Campus, Selayang, Selangor, Malaysia
Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Sungai Buloh Campus, Selayang, Selangor, Malaysia
Nornazirah Azizan, Department of Pathology and Microbiology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
Department of Pathology and Microbiology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia