Waldenström Macroglobulinemia Mimicking A Primary Lung Carcinoma

Waldenström Macroglobulinemia Mimicking Lung Cancer

Abstract

Waldenström macroglobulinemia (WM) is a rare hematological disease that accounts for 1-2% of non-Hodgkin lymphomas. WM is a variant of lymphoplasmocytic lymphoma and is characterized by bone marrow involvement as well as immunoglobulin M monoclonal gammopathy. It occurs as 3 to 4 cases per million each year. Extramedullary involvement of this entity is rare, and lung involvement may present radiologically as a mass, nodular lesion, diffuse infiltration, or pleural effusion. The diagnosis can be made by performing a biopsy of the pulmonary parenchyma, bronchoalveolar lavage, or cytological examination of pleural fluid. Here, we aimed to present a case of WM mimicking primary lung carcinoma radiologically.