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Introduction: The widespread access of the society to mobile phones and their intensive use cause health concerns. This study is aimed to investigate the possible histopathological effects of exposure to Radio-frequency Radiation (RFR) originating from mobile phones rat heart and spleen tissue.
Methods: Totally 14 Sprague Dawley male rats were used and divided into 2 group (n= 7 for each); sham-control group, exposure group. RFR exposure group was exposed to 2100 MHz GSM-like RFR for 5 hours/day, for 14 days. Heart and spleen tissues of all rats were sampled for histopathological examination and hematoxylin-eosin staining was performed. For p53 examination, immunohistochemical staining was also used in both tissues.
Results: Histopathological and immunohistochemical evaluation revealed no significant changes in heart tissue, but trabecular irregularity and enlargement of sinusoids were observed in the spleen in histopathological evaluation.
Conclusion: It was observed that short-term RFR exposure did not cause significant morphological changes in heart and spleen tissue. This situation may be seen due to the protective effect of the body against RFR.