The Importance of Test Variability in Acute Myeloblastic Leukemia: A Case Report

Authors

  • Ayşegül Öztürk Kaymak Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital
  • Çiğdem Sönmez Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital
  • Büşranur Çavdarlı Ministry of Health Numune Education and Resesarch Hospital
  • Senem Öztomurcuk Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital
  • Nurefşan Talayhan Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital
  • Gülcan Güntaş Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital

Abstract

Acute myeloid leukemia (AML), phenotypically and genotypically is a quite heterogeneous disease. More than 100 cytogenetic aberrations and gene mutations that are specific to this disease are defined (1). A patient who applied to hematology polyclinic of our hospital with various complaints was diagnosed with AML. In genetic analyses, t(8;21) and FLT3-ITD were found to be positive. Additionally, in chromosome analysis trisomy 8 was observed. After remission was ensured in the patient, allogenic stem cell transplantation was carried out. By conducting t(8;21), FLT3 mutation and trisomy 8 analyses on the patient at regular intervals, prior information was gathered about the relapse and minimal residual disease

Author Biographies

Ayşegül Öztürk Kaymak, Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital

Medical genetics

Çiğdem Sönmez, Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital

Biochemistry

Büşranur Çavdarlı, Ministry of Health Numune Education and Resesarch Hospital

Medical genetics

Gülcan Güntaş, Ministry of Health Dr. A. Y. Demetevler Oncology Education and Resesarch Hospital

Biochemistry

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Published

26.10.2014

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