The Effect of Hysteroscopy on Fertility in Women with Unexplained Infertility

Fertility After Hysteroscopy

Abstract

Purpose: This study aims to investigate how undergoing hysteroscopy affects the reproductive rates of the women with unexplained infertility.

Methods: A total of 145 women who were aged between 20 and 40 years, who had been diagnosed with unexplained infertility and who underwent hysteroscopy at the study center between 1 January 2021 and 1 January 2022 were enrolled into this study. All patients who underwent hysteroscopy were put to an 18-month-long follow up period.

Results: The clinical pregnancy rate was 43.4% while live birth rate was 38.6% for this cohort. Average time to pregnancy took 5.6±1.8 months (range: 2-9 months). The mode of conception was unassisted in 28 pregnancies (44.4%) whereas the mode of conception was ovarian hyperstimulation combined with intrauterine insemination in 23 pregnancies (36.5%) and in vitro fertilization in 12 pregnancies (19.1%). The patients who were able to conceive after hysteroscopy had significantly younger age, lower gravidity, and parity than the patients who failed to conceive after hysteroscopy (p=0.008, p=0.005 and p=0.001 respectively). The patients who succeeded to give birth to living newborns after hysteroscopy had significantly younger age, lower gravidity, and parity than the patients who failed to deliver living neonates after hysteroscopy (p=0.040, p=0.003 and p=0.001 respectively). Septum resection was significantly more frequent and adhesiolysis was significantly less frequent in the patients who were able to give birth to living newborns after hysteroscopy (p=0.038 and p=0.014 respectively).

Conclusion: Hysteroscopy appears to have a positive impact on the live birth rates of women with unexplained infertility.