Multi-centric Giant Cell Tumor of the Bone: A Rare Case Report

Kemiğin Multisentrik Dev Hücreli Tümörü

Abstract

The giant cell tumor (GCT) of the bones is a benign but locally aggressive neoplasm that affects the epiphyseal-metaphyseal junction of long bones. It makes %5 of the bone tumors.  Multi-centric giant cell tumor (GCT), consists %1 of the GCT of the bones (3, 4). The pathogenesis has not been identified yet because of the rarity of the multi-centric GCT. Paget disease, Brown tumor, and fibrous dysplasia should come up to mind at clinically and radiologically differential diagnosis. Definitive diagnosis is established by histopathological examination. The potential for the malignancy of giant cell tumors is yet to be clarified. Even the type of treatment is controversial the common surgical treatment is aggressive curettage with intra-operative grafting or cementing. The articles about multi-centric GCT are limited in the literature.