The Medical Importance of Hepcidin: Review

Authors

  • Jalal Abdulkareem Abbas Department of Chemistry, Faculty of Science, Gazi University, Teknikokullar, Ankara 06500
  • Rasim Farraj Muslim Department of Environmental Sciences, College of Applied Sciences-Hit, University Of Anbar, Hit, Anbar 31007
  • Mustafa Nadhim Owaid Department of Heet Education, General Directorate of Education in Anbar, Ministry of Education

Abstract

This review aims to study chemical, medicinal and functional properties of Hepcidin. Hepcidin (small bactericidal peptide) is considered a vital regulator of the iron entry in the blood of mammals. Hepcidin, a 25 amino acids long peptide hormone, has antimicrobial activity, especially in urine. Also, many remarkable results exhibited antibacterial, antifungal and anti-candidal activity against multidrug resistance pathogens, in vitro. The central of its formation is cells of the liver (hepatocytes). The expression of Hepcidin is low when iron stores of the human body are insufficient.

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Published

12.09.2020

Issue

Vol. 31 No. 4 (2020): Gazi Medical Journal

Section

Literature Review With Cases