Estimation of Platelet Parameters and Liver Enzymes During the Ramadan Fasting among Healthy Subjects
Abstract
Background/aim: The aim of this study is to investigate Platelet Parameters and liver enzymes during the fasting in Ramadan month on among healthy subjects.
Materials and methods: Twenty eight subjects (20 female and 8 male) participated in this study. Blood samples from healthy subjects were collected before 5 days of the fasting of Ramadan month and 28th day of the fasting of Ramadan month. Platelet Parameters were analyzed by using fully automatic hematological analyzer and liver enzymes were analyzed spectrophotometer (Biolab kits).
Results: The study in female subject discovered no difference in MPV, PCT, ALT activity, and AST activity, while PLT count, PDW and LPCR decreased during the fasting of Ramadan month. In other hand, the study in male subject discovered a decrease in platelet parameters (PLT, MPV, PDW, PCT and LPCR), while ALT activity increased during the fasting of Ramadan month. Also this study in male subject discovered no difference in AST activity during the fasting of Ramadan month.
Conclusions: This study shows that fasting in the Ramadan month had effect on platelet parameters in males while had effect on PLT, PDW and LPCR in female health. This study shows fasting Ramadan had effect on ALT activity in male.
References
Ziaee V, Razaei M, Ahmadinejad Z, Shaikh H, Yousefi R, Yarmohammadi L, Bozorgi F, Behjati MJ.The changes of metabolic profile and weight during Ramadan fasting. Singapore Med J 2006; 47:409–414.
Ramadan J, Mousa M, Telahoun G. Effect of Ramadan Fasting on Physical Performance, Blood and Body Composition. Med Princ Pract 1995; 4:204–212.
Nematy M, Alinezhad-Namaghi M, Rashed MM, Mozhdehifard M, Sajjadi SS, Akhlaghi S, Sabery M, Mohajeri SA, Shalaey N, Moohebati M, Norouzy A .Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study. Nutr J 2012; 11:69.
Attarzadeh Hosseini SR, Hejazi K, Nikroo H .The Effects of Ramadan Fasting and Physical Activity on Blood Hematological-Biochemical Parameters. Iran J Basic Med Sci 2013; 16:845-49.
Ramadan J, Telahoun G, Al-Zaid NS, ,Barac-Nieto M. Responses to exercise, fluid, and energy balances during Ramadan in sedentary and active males. Nutrition 1999; 15: 735-739.
Al-Hourani HM, Atoum MF, Akel S, Hijjawi N, Awawdeh S .Effects of Ramadan Fasting on Some Haematological and Biochemical Parameters. JJBS 2009; 2: 103-108.
Sarraf-zadegan N, Atashi M, Naderi GH, Asgary S, Fatehifar M, Samarian H, Zarei M .The effect of fasting in Ramadan on the values and interrelations between biochemical, Coagulation and hematological factors. Ann Saudi Med 2000; 20: 377-381.
Attarzadeh Hosseini SR, Motahari Rad M, Hejazi K. The Effects of Ramadan Fasting and Physical Activity on Body Composition and Hematological-Biochemical Parameters. J Fasting Health 2014; 2: 96-103.
Aybak M, Türkoglu A, Sermet A, Denli O .Effect of Ramadan fasting on platelet aggregation in healthy male subjects. European Journal of Applied Physiology 1996; 73: 552-556.
Furuncuoglu Y, Karaca E, Aras S, Yonem A.Metabolic, biochemical and psychiatric alterations in healthy subjects during Ramadan. Pak J Nutr 2007; 6:209-11.
Mohammed Z .The Influence of Ramadan Fasting on Some Hematological and Biochemical Parameters in Healthy Adult Males. Iraqi National J. for Nursing Specialties 2011; 24: 45 - 51.
Fararjeh M, AlJamal A, Faris MAI, Al-Kurd R, Khalil M , Al-Bustanji Y.Effect of intermittent fasting on lipid profile and hematological parameters in healthy volunteers in Jordan. Univers J Med Dent 2012; 1: 005-009.
Nasiri J, Mahmoudzadeh M,Kheiri S, Khoshdel AThe effect of Ramadan fasting on hematological parameters. Iran J Med Sci 2016; 4:145-151.
Elfert AA, AbouSaif SA, Kader NAA, AbdelAal E, Elfert AY, Moez ATA, Elbatae H E, Kohla M S,Salah R A,Elbadry A .A Multicenter Pilot Study of the Effects of Ramadan Fasting on Patients with Liver Cirrhosis. Tanta Medical Sciences Journal 2011;6:33-25.
Nasiri J, Kheiri S, Khoshdel A, Boroujeni AJ .Effect of Ramadan Fast on Liver Function Tests. Iran J Med Sci 2016; 5:459-460.
Unalacak M, Kara IH, Baltaci D, Erdem O, Bucaktepe PG. Effects of Ramadan Fasting on Biochemical and Hematological Parameters and Cytokines in Healthy and Obese Individuals. Metab Syndr Relat Disord 2011; 9:156-61
Shawky S M, Zaid AM , Orabi SH , Shoghy KM, Hassan WA. Effect of Intermittent Fasting on Brain Neurotransmitters, Neutrophils Phagocytic Activity, and Histopathological Finding in Some Organs in Rats. IJRSB 2015;11 : 38-45
Nobili V1, Marcellini M, Devito R, Ciampalini P, Piemonte F, Comparcola D, Sartorelli MR, Angulo P. NAFLD in children: A prospective clinical pathological study and effect of lifestyle advice. Hepatology 2006; 2:458-65.
El-Mitwalli A, Zaher AA, El-Salammohamed MA, Elmenshawi E. The effect of Ramadan fasting on cerebral stroke: a prospective hospital-based study. Egypt J Neurol 2009; 1:51-56.
Sadiya A,Ahmed S,Siddieg H H,Babas I J,Carlsson M. Effect of Ramadan fasting on metabolic markers, body composition, and dietary intake in Emiratis of Ajman (UAE) with metabolic syndrome. Diabetes Metab Syndr Obes 2011; 4: 409–416.
