Mediastinal Hemangiopericytoma with Bone Metastases in a 2.5 Year-old-boy


  • Arzu Okur
  • Faruk Güçlü Pınarlı
  • Ceyda Karadeniz
  • Aynur Oğuz
  • Aylar Poyraz
  • Ömer Uluoğlu
  • Serdar Kula
  • Rana Olguntürk


Hemangiopericytoma (HPC) is a soft tissue sarcoma characterized by the proliferation of capillary pericytes. Here we present a 2.5 year-old-boy with a mediastinal mass and multiple bone metastases. The tumor was very aggressive and showed progression despite aggressive chemotherapy, leading to a dismal prognosis. 


Stout AP, Murray MR. Hemangiopericytoma: a vascular tumor featuring Zimmerman's pericytes. Ann Surg 1942;116:26-33.

Ferigo N, Cottalorda J, Allard D, et al. Successful treatment via chemotherapy and surgical resection of a femoral hemangiopericytoma with pulmonary metastasis. J Pediatr Hematol Oncol 2006:28:237-40.

Rodriguez-Galindo C, Ramsey K, Jenkins JJ, et al. Hemangiopericytoma in children and infants. Cancer 2000; 88:198-204.

Ferrari A, Casanova M, Bisogno G, et al. Hemangiopericytoma in pediatric ages: a report from the Italian and German Soft Tissue Sarcoma Cooperative Group. Cancer 2001;:92:2692-8.

Yousem SA, Hochholzer L. Primary pulmonary hemangiopericytoma. Cancer 1987;59:549-55.

Johnson JA 3rd, Warren ET, Heath BJ. Primary pulmonary hemangiopericytoma in a 3-year-old child. Tex Heart Inst J 1992;19:146-7.

Raafat F, Cameron AH, Mann JR, et al. Recurrent hemangiopericytoma of the chest wall: report of a case in a 5-year-old boy. Pediatr Pathol 1994;14:19-25.

Simonton SC, Swanson PE, Watterson J, et al. Primary mediastinal hemangiopericytoma with fatal outcome in a child. Arch Pathol Lab Med 1995;119:839-41.

Horikawa-Kyo Y, Tanaka T, Tanano H, et al. Mediastinal hemangiopericytoma. Pediatr Blood Cancer 2009;53:206-7.

Atkinson JB, Mahour GH, Isaacs H Jr, et al. Hemangiopericytoma in infants and children. A report of six patients. Am J Surg 1984;148:372-4.




Most read articles by the same author(s)

<< < 1 2