Lipoprotein (a) and preeclampsia Is Serum Lipoprotein (A) Level Elevated in Preeclampsia Patients?

Lipoprotein (a) and preeclampsia

  • Tolga Ecemiş
  • Coşkun Şimşir
  • Selen Sakar Ecemiş
  • Özge Şehirli Kinci
  • Orhan Gelişen

Abstract

Aim: To examine the serum Lipoprotein (Lp) (a) levels in preeclamptic cases and its relation with the severity of preeclampsia. Materials and Methods: Forty cases over 28 gestational weeks were included in this study, out of which 10 had mild preeclampsia (group 1), 10 had severe preeclampsia (group 2) and 20 were women with normal pregnancy (group 3). Platelet count, levels of total protein, albumin, fibrinogen, serum Lp (a) and prothrombin time were compared between the groups. Results: Significant differences were found between the groups as regards total protein, albumin and platelet values (p<0.001, p<0.001, and p:0.03, respectively). In fibrinogen values and prothrombin time however, no significant differences were observed (p=0.8, and p=0.3, respectively). Significant differences were not observed between the groups upon evaluation of Lp (a) (group 1: 21.5±17.1 mg/dl; group 2: 15.7±8.5 mg/dl; and group 3: 27.6 ±20 mg/dl; p=0.1). Conclusion: No marked differences were observed in the Lp (a) serum concentration between the preeclamptic patients and the control group; and it was shown that it was not associated with the severity of the disease.
Published
2020-03-10
Section
Original Research