Granular Cell Tumor Seen in Buccal Sulcus: A Case Report

  • Özgün Yıldırım
  • Mustafa Öztürk
  • Emre Barış

Abstract

Granular cell tumor is a rare, benign tumor that usually occurs as a single nodule in the skin, tongue or oral cavity. Granular cell tumor is a rare tumor in the head and neck region and most commonly occurs in the oral cavity, especially in the tongue. Although the lesion is usually seen as a solitary nodule with no boundaries, it can be found in different parts of the body. Abrikossoff thought that the tumor is firstly originated from muscle tissue and was called granular cell myoblastoma. Recent ultrastructural studies and stains such as S100 and neuron specific enolase confirm that this tumor is derived from Schwann cells of the peripheral nerves. A 50 year old female patient was admitted to the Department of Oral and Maxillofacial Surgery of Gazi University Dentistry Faculty due to a yellowish white colored, nodular lesion in the left maxillary buccal sulcus area which has been for about 6 months. Histopathological examination of the excised lesion was revealed a granular cell tumor, which was especially seen on the tongue in the oral cavity. No recurrence was observed at postoperative sixth month.

Author Biographies

Özgün Yıldırım
Departmant of oral and maxillofacial surgery
Mustafa Öztürk
Departmant of oral and maxillofacial surgery
Emre Barış
Department of Oral Pathology

References

Suchitra G, Tambekar KN, Gopal KP. Abrikossoff's tumor of tongue: Report of an uncommon lesion. J Oral Maxillofac Pathol 2014;18(1):134–136.

Ferreira JCB, Leite AFO, Guidi R, Mendonça EF. Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report. Ferreira et al. BMC Res Notes 2017;10:14.

Tamborini F, Cherubino M, Scamoni S, Valdatta LA. Granular Cell Tumor of the Toe: A Case Report. Hindawi Publishing Corporation Dermatology Research and Practice. Volume 2010, Article ID 184125, 3 pages.

Daniels JSM. Granular cell tumour of tongue: A case report. The Saudi Dental Journal. 2009;21:75-78.

Loo SV, Thunnissen E, Postmus P, Waal I. Granular cell tumor of the oral cavity; a case series including a case of metachronous occurrence in the tongue and the lung. Med Oral Patol Oral Cir Bucal. 2015;20(1):30-3.

Gayen T, Das A, Shome K, Bandyopadhyay D, Das D, Saha A. Granular Cell Tumor: An Uncommon Benign Neoplasm. Indian J Dermatol. 2015;60(3):322.

Dive A, Dhobley A, Fande PZ, Dixit S. Granular cell tumor of the tongue: Report of a case. J Oral Maxillofac Pathol 2013;17(1):148.

Costa NCS, Bertini F, Carvalho YR, Almeida JD, Cavalcante ASR. Granular cell tumor presenting as a tongue nodule: two case reports. Journal of Medical Case Reports. 2012;6:56.

Akkaya H, Toru HS, Ayva ES, Karabulut Z, Durusoy Ç. Metachronous Occurrence of Granular Cell Tumor in Breast Skin and Scalp: Diagnostic Challenging Differentiating Benign from Malignant and a Literature Review. Hindawi Publishing Corporation Case Reports in Pathology Volume 2016, Article ID 8043183, 6 pages.

Sirera BV, Zabala P, Mira CA, Sempere FJV. Multiple granular cell tumors with metachronous occurrence in tongue and vulva. Clinicopathological and immunohistochemical study. J Oral Maxillofac Pathol 2014;18(3):437–441.

Published
2020-09-12