Gliomatosis Cerebri Mimicking Encephalopathy in a Teenager Boy

Authors

  • Bilgen Işık Department of Pediatrics, Division of Pediatric Hematology and Oncology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Ummügülsüm Gümüş Department of Radiology, Division of Pediatric Radiology, Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Alper Özcan Department of Pediatrics, Division of Pediatric Hematology and Oncology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Ebru Yılmaz Department of Pediatrics, Division of Pediatric Hematology and Oncology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Fatma Türkan Mutlu Department of Pediatrics, Division of Pediatric Hematology and Oncology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Özlem Canöz Department of Pathology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Hakan Gümüş Department of Pediatrics, Division of Pediatric Neurology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Mehmet Akif Özdemir Department of Pediatrics, Division of Pediatric Hematology and Oncology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Hüseyin Per Department of Pediatrics, Division of Pediatric Neurology,Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey
  • Ekrem Unal Department of Pediatrics, Division of Pediatric Hematology and Oncology, Erciyes University, Faculty of Medicine, 38010 Melikgazi, Kayseri, Turkey & Molecular Biology and Genetic Department, Gevher Nesibe Genom and Stem Cell Institution, Genome and Stem Cell Center (GENKOK), 38010, Erciyes University, Melikgazi, Kayseri, Turkey

Abstract

Gliomatosis cerebri (GC) is a diffuse glial tumor of the brain which infiltrates more than two cerebral lobes; and generally seen in adults. Here we present a teenager boy who is diagnosed with gliomatosis cerebri. A 13-years old boy suffered from altered mental status and headache. Cranial edema and herniation was seen at cranial computerized tomography. Magnetic resonance image findings showed left dominance bilateral changes. Pathologic analysis of brain biopsy was relevant with gliomatosis cerebri. We would like to emphasize that gliomatosis cerebri should be considered in the differential diagnosis in patients who presented with abnormal neurological signs, and no clinical and laboratory evidence of infection, in the presence of diffuse brain involvement on the radiological imaging studies.

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Published

06.12.2020

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