Antibiotic Resistance Rates of Acinetobacter Baumannii Strains Isolated from Various Clinical Samples in Giresun Prof. Dr. Atilla ilhan Ozdemir State Hospital

  • Şahin Direkel Giresun University Faculty of Medicine, Department of Medical Microbiology, Giresun, Turkey
  • Emel Uzunoğlu Prof. Dr. Atilla Ilhan Ozdemir State Hospital Medical Microbiology Laboratory, Giresun, Turkey.
  • Selma Keleş Prof. Dr. Atilla Ilhan Ozdemir State Hospital Medical Microbiology Laboratory, Giresun, Turkey.
  • Kürşad Yapar Giresun University Faculty of Medicine, Department of Medical Pharmacology, Giresun, Turkey
Keywords: Acinetobacter baumannii, antimicrobial drug resistance, intensive care units, colistin, tigecycline, multidrug resistance

Abstract

Objective: The aim of this study is to determine the types of specimens, distribution among clinics and antibiotic susceptibilities of 531 Acinetobacter baumannii strains isolated in our laboratory between January 2012-June 2014.Methods: Acinetobacter baumannii isolates were identified by conventional methods and API 20 NE (bioMerieux, France), antibiotic susceptibility tests were performed according to the Clinical and Laboratory Standards Institute guidelines except tigecycline evaluated according to Food and Drug Administration guidelines.Results: Strains were isolated from Anesthesiology and Reanimation Unit (36.9 %), Medical Intensive Care Unit (17.9 %), Neurological Intensive Care Unit (14.7 %), Surgical Intensive Care Unit (13.9 %), Coronary Intensive Care Unit (2.3 %), Internal Medicine Services (9.8 %) and Surgical Services (4.5 %). Specimen types were; 239 (45.0 %) tracheal aspirate, 92 (17.3 %) urine, 78 (14.7 %) blood, 55 (10.4 %) wounds, 38 (7.1 %) sputum and 29 (5.5 %) catheter. The antibiotic resistance rates were found as 99.1 % for nitrofurantoin, 98.9% for cefotaxime, 97.7 % for tetracycline, 97.4 % for piperacillin, 97.2 % for netilmicin, 94.9 % for ceftazidime, 94.7 % for cefepime, 92.8 % for piperacillin/tazobactam, 91.7 % for ampicillin/sulbactam and ciprofloxacin, 91.1 % for meropenem, 89.8 % for imipenem, 89.5 % for levofloxacin, 82.1 % for gentamicin, 81.2 % for trimethoprim/sulfamethoxazole, 79.3 % for amikacin, 69.5 % for cefoperazone-sulbactam, 25.4 % for tobramycin, 5.1 % for tigecycline and 0.8 % for colistin.Conclusion: Our strains were found as sensitive to colistin, tigecycline, tobramycin and cefoperazone/sulbactam antibiotics. Resistance to carbapenems and other antibiotics were remarkable.

Author Biographies

Şahin Direkel, Giresun University Faculty of Medicine, Department of Medical Microbiology, Giresun, Turkey
Department of Medical Microbiology
Emel Uzunoğlu, Prof. Dr. Atilla Ilhan Ozdemir State Hospital Medical Microbiology Laboratory, Giresun, Turkey.
Medical Microbiology Laboratory
Selma Keleş, Prof. Dr. Atilla Ilhan Ozdemir State Hospital Medical Microbiology Laboratory, Giresun, Turkey.
Medical Microbiology Laboratory
Kürşad Yapar, Giresun University Faculty of Medicine, Department of Medical Pharmacology, Giresun, Turkey
Department of Medical Pharmacology

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Published
2015-07-02
Section
Original Research