EDTA-Dependent Pseudothrombocytopenia in an Elderly Patient with Rheumatoid Arthritis: A Case Report

  • Sema Akinci Ataturk Research and Training Hospital, Hematology
  • Kamile Silay Yildirim Beyazit University, Geriatrics
  • Tekin Güney Ataturk Research and Training Hospital, Hematology
  • Aysun Yıkılmaz Yildirim Beyazit University, Hematology
  • Imdat Dilek
Keywords: EDTA-dependent pseudothrombocytopenia, rheumatoid arthritis


 EDTA-dependent pseudothrombocytopenia (EDTA-PTCP) is a phenomenon caused by EDTA- dependent anti-platelet antibody. It is necessary for clinicians to consider the possible presence of PTCP in cases of patients having low platelet counts without any hemorrhagic tendency. We here present a EDTA-dependent pseudothromboctyopenia case which might be associated with rheumatoid arthritis and/or the medications such as sulfasalazine, leflunomide and methylprednisolone. As a conclusion pseudothrombocytopenia should be excluded in all thrombocytopenic patients without any hemorrhagic tendency by manual peripheric smear to avoid unnecessary diagnostic tests and wrong treatments. 


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