Kawasaki Disease with Hidden Neuroblastoma
Abstract
Kawasaki disease, predominantly affecting infants and young children, is a systemic vasculitis with an unknown origin. The diagnosis of the disease is based on clinical criteria. Neuroblastoma is the most common extracranial solid tumor seen children under five years of age as Kawasaki disease. The two conditions are rarely reported together. We describe an infant who was initially diagnosed as Kawasaki disease, and thereafter neuroblastoma. It is discussed whether neuroblastoma plays any role in the pathogenesis of Kawasaki disease in this report.
References
Freeman AF, Shulman ST. Kawasaki disease: summary of the American Heart Association guidelines. Am Fam Physician 2006; 74:1141-48.
Newburger JW, Takahashi M, Gerber MA, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics 2004; 114:1708–33.
Castleberry RP. Predicting Outcome in Neuroblastoma. N Engl J Med 1999; 340:1992-3
Alavi S, Fahimzad A, Jadali F, Ghazizadeh F, Rashidi A. Concurrent adrenal neuroblastoma and kawasaki disease: a report of a rare case. Case Rep Pediatr 2013;931703 (2013:931703. doi: 10.1155/2013/931703)
Lim YJ, Jung JW, Jung HJ, Park JE. Two cases of Kawasaki disease with hidden neuroblastoma. Indian J Pediatr 2013; 80:881-8.
Yanagisawa M, Kobayashi N, Matsuya S. Myocardial infarction due to coronary thromboarteritis following acute febrile mucocutaneous lymph node syndrome in an infant. Pediatrics 1974; 54:277–80.
Zhang YT, Feng LH, Zhong XD, Wang LZ, Chang J. Kawasaki disease associated with neuroblastoma: evidence for a new paraneoplastic syndrome? Indian J Pediatr 2014; 81: 403.
Tanaka N, Naoe S, Masuda H, Ueno T.Pathological study of sequelae of Kawasaki disease (MCLS). With special reference to the heart and coronary arterial lesions. Acta Pathol Jpn 1986; 36: 1513-27.
Ohta S, Narita T, Kato H, Taga T, Takeuchi Y. A patient with Kawasaki disease who developed acute urinary retention due to pelvic neuroblastoma. Eur J Pediatr 2002; 161: 631.
