Advanced Triple Negative Breast Cancer in Pregnancy

  • Firdaus Hayati
  • Tze Huat Chong Department of Surgery, Serdang Hospital, Ministry of Health Malaysia, Serdang, Selangor, Malaysia
  • Gunaseelan G. Durairaj Department of Surgery, Serdang Hospital, Ministry of Health Malaysia, Serdang, Selangor, Malaysia
  • Nornazirah Azizan Department of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
  • Fatimah Ahmedy Department of Medical Education, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
  • Nor Faezan Abdul Rashid Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia

Abstract

Breast cancer is one of the most common prevalent malignancies in pregnancy. The management is challenging as it involves both maternal and fetal well-being. A 41-year-old lady was diagnosed with triple negative breast cancer in the second trimester pregnancy. Neoadjuvant chemotherapy was decided as she opted for a continuation of pregnancy and refusal for mastectomy. After completing the second cycle of chemotherapy, she developed preterm premature rupture of membrane and had fetal malposition requiring an emergency caesarean section. Computed tomography staging revealed an advanced disease, hence needing palliative treatment and support. The difficulties in managing this case arise in choosing the best treatment to preserve both maternal and fetal wellbeing.

Author Biographies

Tze Huat Chong, Department of Surgery, Serdang Hospital, Ministry of Health Malaysia, Serdang, Selangor, Malaysia
Department of Surgery, Serdang Hospital, Ministry of Health Malaysia, Serdang, Selangor, Malaysia
Gunaseelan G. Durairaj, Department of Surgery, Serdang Hospital, Ministry of Health Malaysia, Serdang, Selangor, Malaysia
Department of Surgery, Serdang Hospital, Ministry of Health Malaysia, Serdang, Selangor, Malaysia
Nornazirah Azizan, Department of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
Department of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
Fatimah Ahmedy, Department of Medical Education, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
Department of Medical Education, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
Nor Faezan Abdul Rashid, Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia
Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia
Published
2020-09-12