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Aim: The aim of this study was to investigate whether there is a relation between ABO blood groups and pain levels during venoblock procedure to vena saphena magna using N-butyl cyanoacrylate (NBCA), as well as need of analgesics in the postoperative period in patients with venous insufficiency.
Materials and Methods: Fifty patients from each of the A, B, AB and O blood groups were included in the study. The severity of pain during ablation with NBCA was measured using the Visual Analogue Scale (VAS) score. In addition, all patients were asked how many days they used analgesics after the procedure at the fifth day visit. VAS scores and postoperative analgesic requirements were evaluated according to ABO blood groups.
Results: Both VAS scores and the days of analgesics need after procedure in the B and AB blood groups were significantly higher than in the A and O blood groups (p <0.001), however, were not different between B and AB blood groups. They were significantly higher in blood group 0 were than in blood group A (p <0.001) but were significantly lower thanB and AB blood groups (p <0.001). The VAS scores and days of analgesics need of patients with A blood group were the lowest among all blood groups (p <0.001).
Conclusion: We demonstrated that pain levels occurred during venablock procedure and postoperative analgesic need were related to ABO blood group. Accordingly, the relationship between pain and blood group may contribute to pain management for both diagnostic and therapeutic purposes.