Vomiting may be the Only Sign of Cystic Fibrosis: A Case Report

  • Husniye Yucel
  • Meltem Akcaboy Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital
  • Melek Melahat Oguz
  • Engin Demir
  • Saliha Senel
Keywords: Cystic fibrosis, hypokalemic hypochloremic alkalosis, Pseudo-Bartter syndrome

Abstract

Cystic fibrosis has variable clinical presentations at different ages. We present here a-7-month-old boy admitted with vomiting, hypokalemia, hyponatremia, hypochloremia and metabolic alkalosis that corresponded to a pseudo-Bartter syndrome. He had been hospitalized twice because of vomiting of unknown origin. A sweat test had already been performed and the result was normal. He had been admitted to our pediatrics unit for diagnostic work-up. Reevaluation of physical examination, serum electrolytes, blood gases and cystic fibrosis mutation analysis finally led to a diagnosis of cystic fibrosis. We planned to call the attention to the often disregarded message that vomiting may be the only sign of cystic fibrosis. Sometimes invasive tests planned to investigate the etiology of vomiting should be postponed.

References

Koshida R, Sakazume S, Maruyama H, et al. A case of pseudo-Bartter's syndrome due to intestinal malrotation.ActaPaediatrJpn 1994;36:107-11.

Yalçin E, Kiper N, Doğru D, Ozçelik U, Aslan AT.Clinical features and treatment approaches in cystic fibrosis with pseudo-Bartter syndrome. Ann Trop Pediatr 2005;25:119-24.

Yılmaz E, Erdem H, Özgüç M, et al. Study of 17 mutations in Turkish cystic fibrosis patients. Human Heredity 1995;45:175-7.

Fustik S, Pop-Jordanova N, Slaveska N, Koceva S, Efremov G. Metabolic alkalosis with hypoelectrolytemia in infants with cystic fibrosis. PediatrInt 2002;44:289-92.

Beckerman RC, Taussig LM. Hypoelectrolytemia and metabolicalkalosis in infants with cystic fibrosis. Pediatrics 1979;63:580-3.

Halicioglu O, Akman SA, Sutcuoglu S, Coker I.Diverse genotypical features and impacts on clinical course and severity of cystic fibrosis: early childhood experience.Minerva Pediatr 2011;63:169-75.

Published
2018-06-19