Breast Cancer Metastasis Mimicking Cholangiocarcinoma: A Case Report

  • Hasan Bostanci Gazi University
  • Mahir Nasirov Gazi University
  • Cagri Ahmet Buyukkasap Gazi University
  • Kursat Dikmen Gazi University
  • Hande Koksal Gazi University
  • Mustafa Kerem Gazi University
Keywords: Breast cancer, metastasis, bile ducts


Breast cancer is the most common tumor and the main cause of death for malignancy in women. Common sites of metastasis include bones, lungs, lymph nodes, liver and brain. Although widespread metastases can compress or infiltrate the bile ducts, direct metastatic involvement of extrahepatic bile ducts are rare. Herein we present a patient with a history of breast cancer who is an exceptional case with metastatic infiltration of extrahepatic bile ducts in the absence of hepatic lesions and any other systemic metastasis.  

Author Biographies

Hasan Bostanci, Gazi University
Department of General Surgery
Mahir Nasirov, Gazi University
Department of General Surgery
Cagri Ahmet Buyukkasap, Gazi University
Department of General Surgery
Kursat Dikmen, Gazi University
Department of General Surgery
Hande Koksal, Gazi University
Department of General Surgery
Mustafa Kerem, Gazi University
Department of General Surgery


Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. European journal of cancer (Oxford, England : 1990). 2010 ;46:765-81.

Petracci E, Decarli A, Schairer C, Pfeiffer RM, Pee D, Masala G, et al. Risk factor modification and projections of absolute breast cancer risk. Journal of the National Cancer Institute. 2011;103:1037-48.

Coletta M, Montalti R, Pistelli M, Vincenzi P, Mocchegiani F, Vivarelli M. Metastatic breast cancer mimicking a hilar cholangiocarcinoma: case report and review of the literature. World journal of surgical oncology. 2014 16;12:384.

Markelov A, Taheri H, Vunnamadala K, Ibrahim G. Biliary dyskinesia as a rare presentation of metastatic breast carcinoma of the gallbladder: a case report. Case reports in pathology. 2011;2011:806570.

Menias CO, Surabhi VR, Prasad SR, Wang HL, Narra VR, Chintapalli KN. Mimics of cholangiocarcinoma: spectrum of disease. Radiographics. 2008;28:1115-29.

Popp JW, Jr., Schapiro RH, Warshaw AL. Extrahepatic biliary obstruction caused by metastatic breast carcinoma. Annals of internal medicine. 1979;91:568-71.

Rego RF, Atiq M, Velchala N, Nevin D, McElreath DP, McKnight WD, et al. Ampullary metastasis from breast cancer: an unusual finding. Endoscopy. 2009;41 Suppl 2:E278-9.