A Case of Two Synchronous Cutaneous Collision Tumors

  • Sebnem Kupana Ayva Baskent University, School of Medicine, Department of Pathology, Ankara
  • Merih Tepeoğlu Baskent University, School of Medicine, Department of Pathology, Ankara
  • Ozgur Gündüz Kırıkkale University, School of Medicine, Department of Dermatology, Kırıkkale
  • İlker Yazıcı Kırıkkale University, School of Medicine, Plastic and Reconstructive Surgery, Kırıkkale
  • Onder Bozdoğan Numune Training and Research Hospital, Department of Pathology, Ankara
Keywords: Basal cell carcinoma, cutaneous collision tumor, malignant melanoma, squamous cell carcinoma

Abstract

Cutaneous collision tumors are known as two independent tumors which are close anatomically and separated from one another by well boundaries. We, herein report a 83-year-old female patient with two cutaneous collision tumors in two different localizations at the same time. First cutaneous collision tumor located on left ala nasi was squamous cell carcinoma and basal cell carcinoma and second one located on the right commisure was composed of malignant melanoma (Clark Level IV) and basal cell carcinoma. However, the presence of collision tumors is not uncommon and is often reported in the literature, to the best of our knowledge, it is the first case which shows the association of two synchronous cutaneous collision tumor in the same individual. 

References

Bhatia S, Estrada-Batres L, Maryon T, Bogue M, Chu D. Second primary tumors patient with cutaneous malignant melanoma. Cancer 1999;86:2014-20.

Hallaji Z, Rahimi H, Mirshams-Shahshahani M. Comparison of risk factors of single basal cell carcinoma with multiple basal cell carcinomas. Indian J Dermatol 2011;56:398-402.

Giorgi V, Sestini S, Alfaioli B, Carelli G, Carli P. Cutaneous collision tumour (melanocytic naevus, basal cell carcinoma, seborrhoeic keratosis): a clinical, dermoscopic and pathological case report. Br J Dermatol 2005;152:787-90.

Satter EK, Metcalf J, Lountzis N, Elston DM. Tumors composed of malignant epithelial and melanocytic populations: a case series and review of the literatüre. J Cutan Pathol 2009;36:211-9.

Papa G, Grandi G, Pascone M. Collision tumor of malignant skin cancers: A case of melanoma in basal cell carcinoma. Pathol Res Pract 2006;202:691-4.

Hirakawa E, Miki H, Kobayashi S, Nomura Y, Ohmori M. Collision tumor of cutaneaous malignant melanoma and basal cell carcinoma. Pathol Res Pract 1998;194:649-53.

Piérard GE, Fazaa B, Henry F, Kamoun MR, Piérard- Franchimont C. Collision of primary malignant neoplasms on the skin: the connection between malignant melanoma and basal cell carcinoma. Dermatology 1997;194:378-9.

Burkhalter A, White WL. Malignant melanoma in situ colonizing basal cell carcinoma. A simulator of invasive melanoma. Am J Dermatopathol 1997;19:303-7.

Belisle A, Gautier MS, Ghozali F, Plantier F, Wechsler J. A Collision Tumor Involving Basal Cell Carcinoma and Lentigo Maligna Melanoma. Am J Dermatopathol 2005;27:319-21.

Slaughter DP, Southwıck HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 1953;6:963-8.

Published
2017-03-29