The evaluation of Accu-Chek Inform II® and Hexokinase Method in Emergency Departments for Glucose Measurement

  • Çiğdem Sönmez
  • Arzu Duyar Babacan
  • Nedim Akkaya
  • Ayşegül Öztürk Kaymak
  • Güler Şaşmaz
  • Kadir Okhan Akın
Keywords: Error grid analysis, glucose, hexokinase, point of care testing

Abstract

Objective: Glycemic control has a critical role especially in surgical and medical intensive care units and emergency departments (ED), so point-of-care (POC) glucose monitoring has become increasingly important. The aim of our study was to compare the glucose levels of emergency patients, measured with the Accu-Chek Inform II® and hexokinase reference method.Methods: One-hundred-four patients’ glucose levels were studied with hexokinase method in Abbott Architect C16000 device and Accu-Chek Inform II®. The results were analyzed with Error Grid method. Agreement between the systems was assessed using Bland- Altman and Passing-Bablok regression analysis.Results: Among 104 patients, the mean participant age was 43.6 ± 15.7 years. Mean glucose levels measured with Accu-Chek Inform II® glucose and reference method were 180.67mg/dL ± 12.57 and 194.26mg/dL ± 14.55, respectively. There was no statistically significant difference between the groups (P>0.05). These two systems’ R2 value was found to be 0.967 (95% CI, 0.952-0,977). The regression equation was Y=9,46+0.88213X. The error grid analysis showed that 98% of the results fell in the Zone A (89%) and Zone B (9%). Two percent of the results was located in Zone C.Conclusion: The performance of the Accu-Chek Inform II® System was found to be reliable according to currently used reference methods in central laboratories. 

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Published
2015-04-14
Section
Original Research