Determination of Throat Carriage Rate of Group A Beta Hemolytic Streptococci Among Different Age Groups

  • Ebru Evren Baskent University Faculty of Medicine Department of Medical Microbiology
  • Alara Akdeniz
  • Selin Dibooğlu
  • Berk Halilbeyoğlu
  • Ege İleri
  • Merve Kuş
  • Utkun Moran
Keywords: Group A beta hemolytic Streptococci, carriage, throat culture, infection, prevalence

Abstract

Objective: To determine the throat carriage rate of Group A Beta Hemolytic Streptococci among different age groups.Methods: A total of 259 participants from Başkent University Private Ayşeabla School first grade students, Başkent University Faculty of Medicine and Dentistry first and second phase students were enrolled in this study. Informed consent was obtained from all participants. The presence of any upper respiratory system infection symptoms, drug use, Group A Beta Hemolytic Streptococci (GAS) history, family carriage history, socio-economic status were determined by using a questionnaire. Throat culture specimens were obtained with a cotton-tipped swab containing transport medium, transported to the laboratory within two hours, and processed in the same day with standard techniques. For data analysis Pearson's Chi-square and Monte Carlo simulation Chi-square tests were used.Results: Out of 259 samples GAS was determined from only two samples (about 1%) in two adults. Carriage was not determined among school children. GAS cases were seen in a girl and a boy between 18-19 ages. There was no statistically significant difference in terms of carriage rate between girls and boys.Conclusion: Better socio-economic status and hygiene conditions and also changing climate seem to be important factors than age. 

References

Bisno AL, Gerber MA, Gwaltney Jr JM, Kaplan EL, Richard H, Schwartz RH. Practice Guidelines for Streptococcal Pharyngitis. CID 2002;35:113-25.

Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clin Infect Dis 2012; 55:e86-102.

Hızel K, Emekdaş G,Coşguner M, Altanlar N, Akın A. Kreş ve İlkokul Çocuklarında A Grubu Beta Hemolitik Streptokok Taşıyıcılığı. Turkiye Klinikleri J Pediatr 1997;6:158-60.

Öngen B. A Grubu Streptokok İnfeksiyonlarında Bakteriyolojik Tanı. ANKEM Derg 2004; 18: 45-50.

Parlakay AO, Uysal M, Kara A. Group A streptococcal tonsillopharyngitis burden in a tertiary Turkish hospital. The Turkish J Pediatr 2012;54:474-7.

Elli M, Canter B, Citak C, Tunaoglu S, Dogan M. Invasive Group A Beta-Hemolytic Streptococcal Infection In Children In The 2000’s: A case report Gazi Medical Journal 2008; 19: 84-6.

Cohen-Poradosu R, Kasper DL. Group A streptococcus epidemiology and vaccine implications. Clin Infect Dis. 2007;45: 863-5.

Tanz RR, Shulman ST. Chronic pharyngeal carriage of group A Streptococci. Pediatr Infect Dis J 2007; 26:175-6.

Bargh GJ, Hoch JS, Speechley M, Willey BM, McGeer A, Hwang SW. A streptococcal carriage among residents of an urban homeless shelter. Letter to the editor. Can J Infect Dis Med Microbiol 2007;17:316-8.

Engel ME, Mayosi BM. Clinical and epidemiological aspects of Streptococcus pyogenes pharyngitis and carriage in Africa. SA Heart Journal 2013;10:434-9.

Pichichero ME, Marsocci SM, Murphy ML, Hoeger W, Green JL, Sorrento A. Incidence of streptococcal carriers in private pediatric practice. Arch Pediatr Adolesc Med 1999;153:624-8.

Sevinc I, Enoz M. The Prevalence of Group A Beta-hemolytic Streptococcus in Healthy Turkish Children in Day-care Centers in Ankara. Chang Gung Med J. 2008;31:554-8.

Shaikh N, Leonard E, Martin JM. Prevalence of Streptococcal Pharyngitis and Streptococcal Carriage in Children: A Meta-analysis. Pediatrics 2010;126:557–64.

Adiloğlu AK, Can R, Kaya S, Cicioğlu Arıdoğan B. Isparta ili Kesme Köyünde 15-60 yaş arası gönüllülerde boğaz sürüntü örneklerinin incelenmesi. Türk Mikrobiyol Cem Derg. 2002;32:193-6.

Abdissa A, Asrat D, Kronvall G, Shitu B, Achiko D, Zeidan M et al. Throat carriage rate and antimicrobial susceptibility pattern of group A Streptococci (GAS) in healthy Ethiopian school children. Ethiop Med J. 2011;49):125-30.

Öztürk CE, Yavuz T, Kaya D, Yücel M. The rate of asymptomatic throat carriage of group A Streptococcus in school children and associated ASO titers in Duzce, Turkey. Jpn J Infect Dis. 2004;57:271-2.

Toprak D, Demirdal T, Aşçı Z, Orhan S, Çetinkaya Z, Demirtürk N. Sağlıklı okul çocuklarında nazofarinkste A grubu beta hemolitik streptokok taşıyıcılığı. Düzce Tıp Fakültesi Dergisi 2008;2:26-9.

Kurtoğlu MG, Berktaş M, Bozkurt H, Bayram Y, Gülmez S. Gündüz Bakımevlerinde A Grubu Beta Hemolitik Streptokok ve Haemophilus Influenzae Taşıyıcılığı. İnfeksiyon Dergisi. 2003;17:281-4.

www.mgm.gov.tr (Access date: May 14 2014).

Published
2014-07-24
Section
Original Research